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Description
More patients receiving tirzepatide discontinued treatment due to GI adverse reactions than patients receiving placebo during all clinical trials

The goal is the minimum effective dose, not the maximum tolerable dose

Herker, E

Some men find weekend dosing preferable, managing any symptoms on days without work obligations
doi: 10.1111/j.2042-7158.1996.tb05869.x

combination efficacy and long-term safety remain unmeasured
