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Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604

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AOD 9604 2mg High-Purity Peptide for Metabolic Studies AOD 9604 is a peptide derived from Growth Hormone, intended for use in scientific research focusing on metabolic processes

Cell Res 29:343344 Grotemeyer A, McFleder RL, Wu J, Wischhusen J, Ip CW (2022) Neuroinflammation in Parkinsons diseaseputative pathomechanisms and targets for disease-modification