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No significant adverse effects have been reported in clinical use at therapeutic doses

For instance, the intestinal secretion of glucagon-like peptide 1 (GLP-1) influences the hypothalamus via the gut-brain axis, inducing insulin secretion, regulating appetite, and energy metabolism

Conclusions The decline in fertility associated with womens increasing age has become a significant issue for modern women [1,2,3,4]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Sakai M., Yu Z., Taniguchi M., Picotin R., Oyama N., Stellwagen D., Ono C., Kikuchi Y., Matsui K., Nakanishi M., et al

J Agric Food Chem (1988) 36:132629