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Proposed model for LB nucleation and growth The existing LB models, namely (1) the aggregation/fibrillization theory and (2) the liquidliquid phase separation model, largely theorize monomeric Syn solely as a precursor with fibrillization as the pathological endpoint, ultimately, LB formation

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Glutathione S-transferase P-mediated protein S-glutathionylation of resident endoplasmic reticulum proteins influences sensitivity to drug-induced unfolded protein response

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MorrisGWalderKRBerkMMarxWWalkerAJMaesMet alThe interplay between oxidative stress and bioenergetic failure in neuropsychiatric illnesses: can we explain it and can we treat it

These data are also consistent with interaction with the positively-charged sulfur center being increasingly favorable in going from neutral to monoanionic to dianionic substituents