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The study concluded that both topical and oral glutathione are effective skin-lightening agents, with the combination therapy potentially offering superior results

J Comp Neurol 373:157172 Lubos E, Loscalzo J, Handy DE (2011) Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities

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- Glutathione when used as a supplement for skin whitening has been shown to be safe and effective in numerous clinical studies, and according to a double-blind placebo-controlled clinical trial by National Institute of Health [1], Glutathione treatment has been proven to significantly lower the skin melanin index of study participants after a few weeks of use

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