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Proline metabolism is important for regulating the survival and death of various types of cancer cells [122]

An indirect evaluation can be made by measuring the levels of vitamin K-dependent coagulation factors, which are below 50% in the presence of vitamin deficiency

In particular, the vitamin can reduce the production of prostaglandin E2, which helps to regulate inflammatory pathways [40]

This limitation hinders research to clarify the dynamic role of metabolites and metabolic rewiring across heterogeneous tissues in health and disease

Akkiraju, H

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