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Br J Dermatol 2008;159:126774

[DOI] [PMC free article] [PubMed] [Google Scholar] 126.Chellappa, K
For example, while use of a relatively low overdose of 200 mg/kg APAP demonstrated protection against liver injury in cyclophilin D-deficient mice [96], only transient protection was achieved when cyclophilin was inhibited using cyclosporine A in vitro [94]

If that wasnt enough, alcohol also disrupts our cytokine system, the small proteins that act as part of our immune system

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Immunologic and endocrine effects of the flame-retardant pentabromodiphenyl ether (DE-71) in C57BL/6 J mice