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Mol Psychiatry 25:26952711

10.1038/s41582-021-00530-8 68 HazlettH

For humans, mechanical ventricular assist pumps, heart transplant and gene therapy are more advanced treatment options, although remain less feasible and unavailable in canine patients at this time

Furthermore, ROS-induced activation of the TGF-/Smad signaling pathway promotes tubulointerstitial fibrosis, further compromising the expression environment of OCTN2 and aggravating carnitine loss [134]

Vitamin C (as sodium ascorbate) 1,000 mg
