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Therefore, GPX8 not only participates in the folding of proteins in the endoplasmic reticulum, exerts the role of oxidative stress, but also participates in the regulation of Ca 2+ in the endoplasmic reticulum

192 While DNA damage often leads to genomic instability and tumorigenesis, damage at the telomeres can promote cell death

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erastin, which depletes cellular glutathione, and RSL3, which inhibits GPX4 activity, and others)

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