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The issue is balance
10.1074/jbc.M208002200 107 LeitchJ
Although GSSG represents approximately 1% of the total glutathione in the cell under basal conditions, a striking increase is found in cells undergoing oxidative stress
doi: 10.1016/j.bjps.2008.03.040
The activation of GPX4 could improve the degradation of the extracellular matrix induced by ferroptosis 14
[DOI] [PubMed] [Google Scholar] 97.Koh S.H., Lee S.M., Kim H.Y., Lee K.Y., Lee Y.J., Kim H.T., Kim J., Kim M.H., Hwang M.S., Song C., Yang K.W., Lee K.W., Kim S.H., Kim O.H
