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Within 5 to 8 days after the dose, the infants experienced significantly increased hemoglobin and reticulocyte counts, normoblastic erythropoiesis, improved mental status, regression of abnormal skin pigmentation, and reduction in tremors.[9] Three hundred sixty-six pregnant women in India received 50 mcg of oral vitamin B 12 or placebo capsules once daily beginning during their first trimester of pregnancy and continuing until 6 weeks postpartum

Some individuals may have difficulty maintaining sufficient vitamin D levels due to limited sun exposure, dietary factors, or certain gastrointestinal conditions that may affect nutrient absorption

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This reduces production of IL-1, IL-6, TNF-, and other cytokines driving chronic oral inflammation
