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Shikonin, a naphthoquinone pigment derived from the traditional Chinese herbal medicine comfrey root, exhibits antioxidative properties, inhibits apoptosis, and promotes the proliferation and differentiation of neural progenitor cells

All of the experiments were approved by the local ethics committee

Figure 4 Another mechanism of cancer cell invasion is the generation of circular chemorepellent-induced defects (CCIDs) in the wall of the LVs (14)

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