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Base solution

Significantly reduced ATP levels and reduced activity in oxidative phosphorylation complexes I and IV of the electron transport chain (ETC) in SZ patient-derived neurons with 22q11.2DS have also been observed [77]

IR is characterized by a poor response to insulin whereby glucose uptake is impaired regardless of insulin levels (Len-Mimila et al., 2021)

For downstream functional assays, iHLCs were replated on day 20 of differentiation

|triggered by chemotherapy
