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10.1016/j.foodchem.2019.05.001 94 ZhuB.ZhaiY.JiM.WeiY.WuJ.XueW.et al (2020)

As the parameters measured did not differ significantly between the two LC doses used, the study concluded that a low dose of LC was sufficient to render positive effects on pregnancy and offspring outcomes in pregnant mice [42]

Trimethylamine-N-Oxide promotes vascular calcification through activation of NLRP3 (Nucleotide-Binding domain, leucine-rich-containing family, pyrin domain-containing-3) inflammasome and NF-B (nuclear factor B) signals

Animal reproduction studies with semaglutide have shown embryofetal toxicity, including structural abnormalities, at exposures below those expected at therapeutic doses in humans