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[DOI] [PMC free article] [PubMed] [Google Scholar] 55

evaluated penile plaques in rat models treated with PDE-5 inhibitors, but also with l-arginine

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L., Lydon, J

Recent drug discovery strategies are based on two criteria: first, compound structures that are distinct from bicalutamide and enzalutamide to avoid cross-resistance and, second, compounds that retain antagonist properties even for known AR mutant proteins that adopt agonist conformations when bound to current AR antagonists (also known as pan-antagonists)