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Yerushalmi R, Woods R, Ravdin PM, Hayes MM, Gelmon KA
This drives massive proton influx into the endosomal compartment

Increased Hunger: Since it works on the ghrelin (hunger hormone) pathway, some patients feel an urge to eat after dosing

The stumbling block has always been that it has to be given IV, in a clinic licensed for administration of intravenous drugs, in order to be effective
