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Other challenges related to fibroblast biology also need to be addressed to achieve optimal translation of melanocortins, as well as other drugs, for the treatment of diseases driven by these cells

perfringens can evade host innate immunity by influencing neutrophils

Key points in dermoscopic differentiation between early acral melanoma and acral nevus

One study comparing NAM ( n = 54) and non-NAM acral melanoma ( n = 78) revealed that, among common melanoma driver genes, mutations in KIT and KRAS were predominantly found in NAM, whereas those in BRAF and NRAS occurred almost exclusively in acral melanoma [18]

doi: 10.1038/s41591-020-01206-4

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