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Consequently, the Trx and Grx systems maintain the balance of thiol-disulfide interactions in the reduction/oxidation conversion of protein forms, which act as target signaling pathways to regulate disulfide stress and may act as crucial triggers to suppress disulfidptosis

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(10) NADPH-dependent thioredoxin-based broad-range disulde reductase sytem (TrxAB)

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