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The third factor involves the molecular response to inflammation and oxidative stress that might originate from other co-existing diseases, such as hypertension, and metabolic disorders, such as diabetes and obesity

Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery

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doi: 10.1111/jre.12661

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39, 954960.10.1111/j.1471-4159.1982.tb12598.x 162 ZwingmannC.BrandA.Richter-LandsbergC.LeibfritzD
