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Description
On/off cycling: the documented pattern is 812 weeks on, then 48 weeks off

Aim for a limit under 4 drinks in 2 hours as a general guideline

This stands in marked contrast to what has happened in different situations in which clinical trials were designed according to predictive biomarkers such as, e.g., trastuzumab in HER2-positive breast cancer patients

And this then could have led to gut leakiness

Most people feel relief within 30 minutes, with effects typically lasting 4-6 hours

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