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4.5 Limitations of this study None of the studies had included the neurofilament light (NfL) chain, which is pathologically confirmed for AD that could be encouraged to include in the findings More research should be carried out specifically using transgenic animals, which may give accurate findings of AD Most of the studies were carried out in a short period of time, since a chronic study should be carried out for a long duration for the analyses and determination of AD The studies included MSG as injectables and not by oral administration, which could be focused on in future research to understand the perspectives in different dimensions More studies on Ki-67 may help to elucidate neurofibrillary degeneration in AD The inability to recognize learning and memory behaviors in neonatal studies A significant body of evidence comes from the same lab and country (Onaolapos lab and Nigeria), which could be considered as a minimal bias 4.6 Precautions suggested Since our daily MSG intake is unknown, we should steer clear from fast foods Rejuvenating the body through detoxification techniques is possible 5 Future directions and implications Amyloid- plaques and tau tangling are the characteristic features of Alzheimers disease