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Regular alcohol consumption burdens the liver, depleting its natural glutathione stores and impeding detoxification. Smoking causes harmful free radicals into the body, further diminishing glutathione's ability to neutralize toxins and protect cells

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BSO+AUR decreased caspase 3/7 activity in HNSCC cells and significantly reduced the viability of both Bax/Bak double knockout (DKO) and DKO-Bax reconstituted hematopoietic cells suggesting that necrosis was involved
