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A portion of the supplement is lost in digestion and first-pass metabolism in the liver

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Considering that animal foods are typically the most effective sources of vitamin B12, those who follow a vegetarian/vegan diet regimen and dont consume any animal products are also most likely to have a deficiency

separation occurs in the terminal ileum in the presence of calcium, and vitamin B 12enters the mucosal cell for absorption

When Injections Become Necessary The normal dose of B12 injection is important for treatment