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2017 reported reduced adipose mass in diet-induced obese mice without changes in food intake

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Titrate: Increase by roughly 100 mcg every 24 weeks as tolerated

10.1016/j.bbrc.2018.04.078 93 MoriV.AmiciA.MazzolaF.Di StefanoM.ConfortiL.MagniG.et al (2014)

As Kannt & Pfenninger highlight in Frontiers in Physiology , maintaining NAD levels is a cornerstone of metabolic health, supporting mitochondrial function and improving resistance to metabolic stress (Kannt & Pfenninger, Frontiers in Physiology )

Raising the KLOW dose to compensate would also raise GHK-Cu excessively