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Description
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Mass Spectrometric Screening of Solvent Extractables from Strain F3876/87 Bacterial pellets, prepared from F3876/87 liquid cultures (100 mL) by centrifugation, were extracted with 10 mL of MeOH, MeCN, or MeCN/H 2 O (70/30, v/v), respectively, by shaking overnight (15 h) at room temperature
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Mechanistically, fragmentation reduces malonyl-CoA inhibition of CPT1, while elongation increases CPT1 sensitivity to malonyl-CoA inhibition

Even more impressive, over 85% of participants receiving the two highest retatrutide doses achieved complete resolution of steatosis, defined as liver fat content dropping below 5%
