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Triglycerides in adipose tissues are used for long-term energy storage in animals Triglycerides can store roughly twice as much energy per gram as carbohydrates and do not contribute to the osmotic pressure of the cell (as they are non-polar) Triglycerides are more difficult to digest (they can only be broken aerobically) and cannot be easily transported due to their hydrophobicity Consequently, triglycerides are more suitable for long-term energy storage whereas carbohydrates (glycogen) are more suitable for short-term energy storage Triglycerides have low thermal conductivity, meaning they have a limited capacity to conduct heat and are effective thermal insulators Mammals living in cold or aquatic environments (such as the ringed seal) will possess thick layers of subcutaneous fat to insulate their internal organs against cold exposure In humans, obese individuals tend to cool less rapidly, however the increased retention of heat makes them more susceptible to heat stress Phospholipids are one of the key structural components of all cell membranes that are responsible for the formation of lipid bilayers Phospholipids consist of a polar head (hydrophilic) composed of a glycerol and a phosphate molecule and two non-polar tails (hydrophobic) composed of fatty acid chains Because phospholipids contain both hydrophilic (water-loving) and lipophilic (fat-loving) regions, they are classed as amphipathic Phospholipids spontaneously arrange into a bilayer with the two hydrophobic tails being shielded from the surrounding polar fluids by the outward facing hydrophilic heads The phospholipid bilayer is only held together by the weak hydrophobic associations between the non-polar tails, making the bilayer both fluid and flexible Because phospholipids contain both hydrophilic (water-loving) and lipophilic (fat-loving) regions, they are classed as amphipathic Steroids are lipids that are composed of four fused carbon rings that are non-polar and lipophilic (fat-loving) Steroids do not resemble other types of lipids (they do not contain a fatty acid chain), but share their basic chemical properties (they are hydrophobic) A steroid hormone is a steroid that functions as a signalling molecule within the body Because they are lipophilic, they can freely diffuse across the phospholipid bilayer and bind to receptors within the target cell However, because they are hydrophobic, they cannot be freely transported within the bloodstream and must be bound to carrier proteins (e.g

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Serum concentrations of RVD1 in patients were significantly lower than in controls (median and IQR= 134.76, 85.35-201.36 pg/mL vs 187.64, 131.01-326.85 pg/mL)