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Molecular liver cancer prevention in cirrhosis by organ transcriptome analysis and lysophosphatidic acid pathway inhibition

For instance, in A549 cells subjected to cigarette smoke extract, luteolin has been found to modulate the CYP2A13/NRF2 and TRPV1/SIRT6 signaling pathways, thereby alleviating oxidative stress and inflammation [226]

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10.1248/bpb.b18-00712 [DOI] [PubMed] [Google Scholar] Lehwald N., Duhme C., Wildner M., Kuhn S., Frst G., Forbes S

Labor-intensive procedures

Within hepatocytes further accumulation leads to deposition in lysosomes (Rhodamine positive staining)
