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4 Mitochondrial DNA: a key player and victim in HIV pathogenesis Mitochondrial DNA (mtDNA) occupies a dual role in HIV pathogenesis: it is both a target for viral-induced damage and a potent activator of innate immune pathways that drive chronic inflammation

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Microbiome study in irradiated mice treated with BIO 300, a promising radiation countermeasure

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In ovarian cancer specifically, a tip-like TEC subset expressing IL13RA1 was found to be enriched in platinum-resistant tumors, suggesting a potential role in resistance through niche remodeling and immune modulation [131]