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This approach does suffer from several limitations, however: the spectral resolution is limited by having to keep each echo readout short, while the later echoes suffer from reduced signal due to T 2 relaxation

267 Numerous HDACs exhibit redox regulation

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Other important players mediating abnormal neuronal transmission in TLE are ligand-gated GABA and glutamate receptors

Cardiac dysfunctions were significantly alleviated in ASC- or caspase-1-deficient mice, or following silencing of either NLRP3 or P2X7, a pyroptosis stimulating ATP receptor [88, 129, 130]