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10.1055/s-0034-1370791 37 JungeC

[DOI] [PubMed] [Google Scholar] 233.Sarker M.K., Lee J.H., Lee D.H., Chun K.H., Jun H.S

Five positions judged to govern ketosteroid isomerase activity based on mutational studies ( The catalytic efficiency of HsaGST A3-3 with 5-AD is 5000-fold higher than that of HsaGST A2-2, and we found that mutating the five residues in the H-site of HsaGST A2-2 into the corresponding HsaGST A3-3 residues enhanced the efficiency to 70% of the HsaGST A3-3 value (Table 1)
