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doi: 10.3389/fonc.2021.812207 188 KasnerMT

To avoid the deleterious effects of high doses of therapeutic drugs on macrophages, drugs can be loaded into liposomes or nanoparticles to enhance their stability, and DOX-loaded PLGA nanoparticles [72] and 7-ethyl-10-hydroxycamptothecin (SN38) nanoparticles [73] delivered by macrophages have shown good antitumor effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 318.Tiss A., Khadir A., Abubaker J., Abu-Farha M., Al-Khairi I., Cherian P., John J., Kavalakatt S., Warsame S., Al-Ghimlas F

A simple explanation for such an apparent paradox is the transfer of glycolysis-derived energy substrates from astrocytes to neurons

a preferred oral formulation thus preferably includes an effective amount of GSH mixed with a stabilizing agent, which is administered under such conditions that the concentration of GSH attained in the lumen of the latter portion of the duodenum is higher than the plasma GSH concentration, and preferably higher than the intercellular concentration of the epithelial lining cells

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