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Archived from the original (PDF) on 17 July 2011
Although targeting macropinocytosis could be a key strategy for overcoming resistance to glutamine uptake blockade, further studies are necessary to examine whether macropinocytosis can overcome tumor cell resistance to glutamine antimetabolites or GLS inhibitors that target enzymes involved directly in glutamine metabolism
[DOI] [PubMed] [Google Scholar] 175.Ben-Dor A., Steiner M., Gheber L., Danilenko M., Dubi N., Linnewiel K., Zick A., Sharoni Y., Levy J
Auranofin, an anti-arthritic drug that has been used clinically for many years, has been shown to significantly influence GPX3 activity, with potential medical implications [208]
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Parr AC, Calabro F, Larsen B, Tervo-Clemmens B, Elliot S, Foran W, et al
