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Morroniside protects dopaminergic neurons from ferroptosis in PD by activating the Nrf2 pathway and upregulating expression of GPX4 and SLC7A11
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In addition, Bcr-Abl can induce autocrine IGF1 signaling in leukemia cells [16]
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doi: 10.1038/ki.2012.180 142 HinrichsGRJensenBLSvenningsenP
Due to the high degree of homology between IR and IGF1R, these receptors share many overlapping downstream signaling pathways (1)
