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Under these conditions, activation of PDH facilitates pyruvate oxidation, attenuates lactate accumulation and restores the NAD+/NADH equilibrium (86)
Zhang Y, Ma WY, Kaji A, Bode AM and Dong Z
However, multiple pathways (multiple hits) are involved in the development of NASH and fibrosis
10.1016/S0092-8674(00)81698-0 Cell 148 JahnR.SchellerR
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