glutathione reductase thiol cycle The role of thiols in antioxidant systems Glutathione-Related Enzymes and Proteins: A

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PQ is principally reduced by Complex I in mitochondria, where PQ induces an increase in the Ca 2+ -dependent permeability of the mitochondrial membrane and forms superoxide

These effects contribute to its potential therapeutic benefits in neurological disorders

Ghaseminejad-Raeini A, Ghaderi A, Sharafi A et al (2023) Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review

The toxicity of the mycotoxin is based on a balance between the rate of primary activation of AFB 1 and the rate of detoxification of primary metabolites or repair of cellular damage, determined by the relative activity of enzymes responsible for these reactions

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