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A therapeutic method is provided comprising treating a mammal subject to hypoxia with an amount of 2(R,S)-D-ribo-(1,2,3,4-tetrahydroxybutyl)thiazolidine-4(R)-carboxylic acid (RibCys) or a pharmaceutically acceptable salt thereof effective to both maintain, restore or increase both the ATP levels and the glutathione (GSH) levels in said tissue.
FOXO4-DRI is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53
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However, since wine consumers are increasingly interested in healthier wines, the wine industry is keen to reduce its use
