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Someone with heart disease, for example, would be a poor candidate since relevant clinical trials havent met the primary endpoints for that use.29 Then there are people for whom SS-31 is contraindicated : women who are pregnant or breastfeeding, and people with a history of cancer

[94] [95] Tadalafil, a phosphodiesterase-5 inhibitor, was considered then rejected by NICE in the UK for the treatment of symptoms associated with BPH

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Excellent dietary sources include : Meat and poultry : beef liver (particularly rich), lamb, chicken, and turkey Fish and seafood : salmon, trout, tuna, sardines, and shellfish (especially clams and mussels) Dairy products : milk, cheese, and yoghurt provide moderate amounts Eggs : particularly the yolk contains bioavailable B12 Fortified foods : breakfast cereals, plant-based milk alternatives, fortified yeast extracts (such as Marmite), and fortified nutritional yeast For individuals following plant-based diets, fortified foods and supplements become essential , as naturally occurring B12 in plant foods is negligible or in forms poorly utilised by humans