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Collectively, these pro-inflammatory cytokines can further exacerbate oxidative stress, creating a self-perpetuating cycle that sustains inflammation and tissue damage

GSH-PXGlutathione peroxidase

The toxicity of dopamine has been demonstrated in a variety of in vitro models, and previous experiments have demonstrated the selective toxicity of dopamine in vivo after exogenous dopamine injection into the striatum, resulting in the selective toxicity of dopamine receptor nerve terminals and the loss of dopaminergic neurons in the substantia nigra [202,203]

Selo MA, Sake JA, Ehrhardt C, Salomon JJ

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