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Many studies have reported that the downregulation of PGC-1 was associated with abnormal mitochondrial biogenesis and diminished ATP production capacity, and the reduced mitochondrial biogenesis in hepatocytes by silica nanoparticles was also associated with the inhibition of the PGC-1/NRF-1/TFAM pathway (81)

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Compatibility and stability of carnitine in parenteral solutions should also be verified to maintain safety and efficacy

elegans The above imaging and biochemical isolation experiments indicate that fat storage structures in wild-type and glo-4 animals possess the same properties as enlarged lipid droplets in mutants defective in peroxisomal function