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DellOsso B, Cafaro R, Ketter TA
RES20400-A7
Metabolic Shift In Hypoxia-Adapted CML Cells and Mechanisms Of Acquired Dasatinib Resistance Uncovered By Proteomic iTRAQ Profiling
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The intense lipid oxidation disrupts ion balance within the cell, leading to reduced membrane flexibility, increased permeability and the formation of protein-based pores
Also in this setting, the potency of FOXO4-DRI was more pronounced when applied in consecutive rounds (Fig
