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The remainder of the precursor then dimerizes through three disulfide bonds and transits into the Golgi where it gets cleaved between the mature cytokine and LAP by protease furin

As-needed protocol: Use DSIP only during periods of elevated stress or sleep difficulty Maintain for 2-4 weeks as needed Discontinue when sleep normalizes This conservative approach treats DSIP as a targeted intervention rather than ongoing supplementation

10.20517/cdr.2019.27 Cancer Drug Resist

It plays a critical role in detoxification, immune support, and cellular repair

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