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To date, we have identified 25 genetically encoded selenoproteins in human, including glutathione peroxidase (GPx), thioredoxin reductase (TXNRD), and iodothyronine deiodinases (DIOs), which have a wide range of functions, from anti-inflammatory and antioxidant activities to thyroid hormone metabolism

Although its dysregulation provides metabolites that favor cancer progression, it also positions the pathway as a promising target for metabolic intervention in cancer

Crozier, A., Jaganath, I.B., Clifford, M.N

10.1038/s41583-018-0091-3 Nat

At Baylor College of Medicine, endocrinologist Dr

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