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[DOI] [PMC free article] [PubMed] [Google Scholar] 222.Newell C., Bomhof M.R., Reimer R.A., Hittel D.S., Rho J.M., Shearer J

1, Supplementary Table 4 show GO enrichments for proteins significant in the relevant categorical model outcomes only)

Mechanistically, the transcription factor zinc finger E-box binding homeobox 1 (ZEB1), a master regulator of the cellular plasticity program epithelial-to-mesenchymal transition, was identified to fine-tune phospholipid composition via direct transcriptional activation of long chain PUFA-generating enzymes FADS2 and ELOVL5, while simultaneously repressing enzymes regulating MUFA/saturated fatty acid (SFA) production

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