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Similarly, NVP-AUY922 has previously shown anti-tumor effects in non-small cell lung cancer and breast cancer, while serving a protective role against RILI in mice [70, 127, 128]

J Nat Prod (1996) 59:11835

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Surface-mediated production of complexed OH radicals and Fe=O species as a mechanism for iron oxide peroxidase-like nanozymes

In normal conditions, 1-5% of O2 in the mitochondrial electron transport chain is not reduced to H2O, CO2 and ATP, stimulating the generation of ROS [H2O2, O2-, nitric oxide (NO) and peroxinitrite] 52