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Description
The reduced enzymatic activity increases cellular concentrations of both substrates that NNMT would otherwise consume: S-adenosyl-L-methionine (the universal cellular methyl donor) and nicotinamide (the NAD + salvage precursor)
PMID 22525653
& Chang, X
But, they work differently in your body
Another study aimed to downregulate the expression of immune checkpoint molecules on T cells using the SIINFEKL peptide vaccine (Jeon et al., 2024)
This report is strengthened by previous published studies by Parthasarathy et al.,71 where methanol intoxication alters immune function
