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Another randomized controlled trial also reported that oral curcumin supplementation (1.5 g/day) for six months improved endothelial function, insulin sensitivity, and metabolic markers associated with atherogenesis (plasma triglycerides, visceral fat, total body fat) in participants with type 2 diabetes (73)

Percentage of time in the open arm was calculated using Ethovision (Noldus)

Therefore, the HK-2 cell line has been generally accepted as a suitable in vitro model for the study of nephrotoxicity in human (Mossoba and Sprando 2020)

Whole-cell recordings with a pipette access resistance less than 20 m and that changed less than 20% during the duration of recording were included

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