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Chronic inflammatory cytokines like interleukin-6 and tumor necrosis factor-alpha can suppress ovarian steroidogenesis by decreasing enzyme activity necessary to produce estrogen and progesterone
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doi: 10.1016/S0140-6736(06)68073-2 98 NaessHSundalEMyhrKMNylandHI

40% of women aged 65-74 and 17% of women aged 75-85 remain sexually active

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