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The expression level of PARP-1 in breast cancer, ovarian cancer, endometrial cancer, lung cancer, skin cancer and non-Hodgkins lymphoma is elevated compared to normal tissues, thus establishing a strong association between parthanatos and these cancers (Harraz et al., 2008

NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction

In addition, adipocytes release metabolic hormones such as leptin and adiponectin, known as adipokines

Leukotriene B4, an inflammatory mediator in gout

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This means precision matters more than quantity