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doi: 10.1096/fasebj.2019.33.1_supplement.822.6

Personalizing Needle Selection Based on Body Composition and Sensitivity Individual factors including subcutaneous fat distribution, skin thickness, injection anxiety, and prior needle experience should guide each patient's needle gauge and length selection, as standardized recommendations don't account for meaningful physiological variation

While there's no official upper limit, doses up to 2,000 mcg can be safely used to treat B12 deficiency under medical supervision

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In general, consult your doctor or pharmacist before taking any medicine

For pregnant people, the American College of Obstetricians and Gynecologists recommends 2.6 micrograms per day of vitamin B12