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The uniqueness of CYP2E1 mediated ethanol metabolism is that it produces acetaldehyde and reactive oxygen species (ROS) as primary metabolites
ACS Pharmacol
In addition, blood levels of other markers possibly associated with cardiovascular disease, such as glucose, cholesterol, triglycerides and C-reactive protein (a marker of inflammation), were also measured
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The bsAbs have a great potential of enhancing the BBB penetration
The current studys light microscopic analysis revealed a significant atrophic and degenerative alteration in the corpora lutea and ovarian follicles in all stages, because DOX-intoxicated animals had a considerably larger mean proportion of atretic follicles and deteriorated corpora lutea than the untreated group
